解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Viruses and other possible causative agents should be sought light and electron microscopically in all cases of ill-defined diseases including "sarcoid." Ideally, tissue should be prepared for electron microscopic examination as soon as a specimen is obtained; however, when this has not been done, tissue preserved in ...
journal_title:Human pathology
pub_type: 杂志文章,评审
doi:10.1016/s0046-8177(83)80164-6
更新日期:1983-10-01 00:00:00
abstract::Primitive neuroectodermal tumors are morphologically similar malignant tumors arising in intracranial and peripheral sites of the nervous system, showing varying degrees of cellular differentiation with a tendency to disseminate along cerebrospinal fluid pathways. They occur primarily in children and young adults. Und...
journal_title:Human pathology
pub_type: 杂志文章,评审
doi:10.1016/s0046-8177(83)80006-9
更新日期:1983-06-01 00:00:00
abstract::Except for post-transfusion hepatitis (PTH), the transmission of disease by blood transfusion appears to be very limited. There are only a few case reports documenting the transmission of malaria and other parasitic diseases, syphilis, or bacterial infections. The ability to eradicate PTH will depend on the developmen...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(83)80024-0
更新日期:1983-03-01 00:00:00
abstract::Granulocyte alloantibodies and autoantibodies have a key role in the pathophysiology of several clinical problems. These include febrile transfusion reactions, severe pulmonary reactions to transfusion, isoimmune neonatal neutropenia, failure of effective granulocyte transfusion, autoimmune neutropenia, drug-induced n...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(83)80022-7
更新日期:1983-03-01 00:00:00
abstract::Improved graft survival was observed in cadaver-kidney recipients prepared with random donor blood transfusions and in selected living-related-kidney recipients primed with transfusions from the kidney donor. This seems to justify a purposeful transfusion policy in these patients. ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(83)80031-8
更新日期:1983-03-01 00:00:00
abstract::Ultrastructural features of bilateral testicular biopsy materials, obtained from both tumor and nontumor areas of the testis of a 27-year-old man with congenital adrenal hyperplasia, revealed a number of pathologic changes. Germ cell hypoplasia and extratubular cellular hyperplasia were noticed in the nontumor portion...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(83)80244-5
更新日期:1983-02-01 00:00:00
abstract::Ultrastructural studies of the brain in three cases of cerebral amyloid angiopathy demonstrated that the vascular amyloid in this disease is composed of fibrils identical to those in systemic amyloid disease, mixed with a large amount of vesicular debris. Amyloid appears to be derived from circulating protein and is d...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(82)80251-7
更新日期:1982-12-01 00:00:00
abstract::Refractile foreign particles within clear vacuoles were observed in capillaries of 17 patients who underwent cardiopulmonary bypass surgery, died, and were autopsied at the George Washington University Hospital from December 1978 through April 1981. The postoperative survival time ranged from less than one day to more...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(82)80243-8
更新日期:1982-12-01 00:00:00
abstract::A case of mucin-positive giant cell carcinoma of the pancreas is presented. Clear cells were a prominent feature of the primary tumor and constituted the majority of the metastatic deposits, a finding not usually associated with pancreatic carcinoma. Results of ultrastructural and histochemical studies are presented, ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(82)80099-3
更新日期:1982-11-01 00:00:00
abstract::A 35-year-old white Jewish homosexual man who had undergone surgery and chemotherapy for an embryonal carcinoma of the testis subsequently developed Kaposi's sarcoma. The neoplasm involved the skin as well as visceral tissues. Tissue derived from a biopsy specimen of one of the skin lesions was used in the in situ hyb...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(82)80063-4
更新日期:1982-10-01 00:00:00
abstract::An unusual case of multiple myeloma in an 88-year-old patient is described. Besides skeletal involvement, there was myeloma of the thoracic and abdominal lymph nodes and of the liver and pancreas. In the pancreas, the myeloma extensively involved the head and body, and on computerized tomography scan was suggestive of...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(82)80057-9
更新日期:1982-10-01 00:00:00
abstract::After multiple fragmentation of neoplastic nuclei into "nucleotesimals," a recently discovered variety of amitosis, some fragments appear to be inflated to full nuclear size; other probably lyse, releasing nucleic acid, which may assist in the synthesis of new cytoplasm around newly formed nuclei. This observation may...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(82)80006-3
更新日期:1982-07-01 00:00:00
abstract::Three cases of veno-occlusive disease of the liver were diagnosed in four autopsied patients who had received high-dose mitomycin C therapy followed by autologous bone marrow transplantation, and the pathologic finding are reported. Review of 27 liver, examined post mortem, of patients receiving other high-dose chemot...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(82)80008-7
更新日期:1982-07-01 00:00:00
abstract::A 64-year-old man with pseudosarcoma of the esophagus is described. Morphologic examinations of this rare tumor were made, and the origin of the sarcoma-like cells of the tumor is discussed. The findings for the sarcoma-like cells of the tumor support the idea that the sarcoma-like elements arose through transformatio...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(82)80036-1
更新日期:1982-05-01 00:00:00
abstract::Two episodes of severe, relapsing sensorimotor polyneuropathy closely paralleled the course of systemic illness in a patient with immunoblastic lymphadenopathy. A review of the literature shows three other cases, although none with documented pathologic changes in muscles and nerves. Based on the pathologic findings i...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(82)80120-2
更新日期:1982-02-01 00:00:00
abstract::In this series of 3,432 cases of malignant melanoma of the choroid and ciliary body, mortality from metastasis 15 years after enucleation was 46 per cent. This mortality was at least ten times greater than has been observed with tumors of the iris, probably owing to the greater size and more malignant cytology of chor...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(82)80116-0
更新日期:1982-02-01 00:00:00
abstract::A 75 year old man presented with metastatic carcinoma of the brain. At autopsy a primary scar adenocarcinoma of the lung was found. By light microscopy the cytoplasm of the tumor cells was seen to contain hyalin masses with tinctorial properties identical to those of the Mallory bodies seen in human alcoholic liver di...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(82)80143-3
更新日期:1982-01-01 00:00:00
abstract::Congenital subclavian steal may result from various anomalies of the aortic arch. The most common predisposing type is the right aortic arch with an isolated left subclavian artery arising from a left ductus arteriosus. A rare variant includes isolation of the left common carotid as well as the left subclavian arterie...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(81)80200-6
更新日期:1981-10-01 00:00:00
abstract::Islets were evaluated for the presence of amyloid deposits in 169 pancreases removed at autopsy. Islet amyloid occurred in 17 of 142 (12 per cent) of nondiabetics and in 16 of 27 (59 per cent) of diabetics. When diabetics were divided into categories according to clinical severity of disease, the insulin treated diabe...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(81)80197-9
更新日期:1981-10-01 00:00:00
abstract::Clinicopathological studies of 181 patients with liver cirrhosis undergoing autopsy in the pathology department of a municipal hospital between 1973 and 1976 are reported. The main etiological types were alcoholic (25.4 per cent), HBsAg positive (14.9 per cent), and cryptogenic cirrhosis (54.7 per cent). Four patients...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(81)80082-2
更新日期:1981-09-01 00:00:00
abstract::The surgical pathologist is often called upon to make a rapid decision about the malignant potential of a soft tissue tumor. These tumors have specific stromas that support growth and endow the tumor with unique qualities, as well as being manifestations of the phenotypic expression of tumor cells. Collagen, the major...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(81)80080-9
更新日期:1981-09-01 00:00:00
abstract::Although mast cell proliferation in the bone marrow frequently occurs in systemic mastocytosis and is often associated with radiographically detectable bone lesions, the pathologic correlates of the skeletal abnormalities are poorly characterized. We therefore examined three nondecalcified transiliac crest biopsy spec...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(81)80084-6
更新日期:1981-09-01 00:00:00
abstract::A six year old boy with bilateral breast enlargement was found to have a normal endocrine status. Resected tissue revealed the features of pseudogynecomastia due to a proliferation of fibrous tissue traversed by neuroid structures. Multinucleated giant cells were present within the fibrous tissue. Ultrastructural stud...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(81)80180-3
更新日期:1981-08-01 00:00:00
abstract::A case of apocrine carcinoma of the breast with psammoma bodies is described in a 69 year old man. The report emphasizes the rarity of this lesion and supports currently held beliefs about the formation of psammoma bodies. ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(81)80178-5
更新日期:1981-08-01 00:00:00
abstract::The peroxidase-antiperoxidase immunohistochemical technique was employed to stain formalin fixed, paraffin embedded tissue sections from three cases of encephalitis caused by Toxoplasma gondii. We studied two cases of congenital infection and one case of acquired toxoplasmosis occurring in an immunocompromised host. T...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(81)80170-0
更新日期:1981-08-01 00:00:00
abstract::Explants from paraspinal muscles of patients with scoliosis were cultured in Millipore diffusion chambers placed in peritoneal cavities of mice. Three and four weeks of incubation produced a predominantly myogenic growth. Cell counts done on paraffin sections and on dissociated cells from the chambers showed that expl...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(81)80046-9
更新日期:1981-07-01 00:00:00
abstract::Geotrichum candidum was identified as an invasive organism in the terminal ileum of a man with "hairy cell" leukemia. The organism was identified on the basis of histologic and cultural characteristics. The diagnostic features of G. candidum infection are compared to those of Aspergillus and Candida species. ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(81)80055-x
更新日期:1981-07-01 00:00:00
abstract::High bone marrow mast cell counts before and after marrow transplantation have been reported to predict graft rejection in aplastic anemia. We tested this association by studying marrow specimens from 73 consecutive patients allografted for severe aplastic anemia, 21 of whom rejected. Mast cell counts per unit area we...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(81)80043-3
更新日期:1981-07-01 00:00:00
abstract::Liver involvement in amyloidosis is rarely associated with intrahepatic cholestasis. The cases recorded in the literature indicate that there is a tendency toward periportal deposition, leading to centrilobular cholestasis. Our case was most interesting in that the amyloid deposition was most severe in the centrilobul...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(81)80029-9
更新日期:1981-05-01 00:00:00
abstract::Giant cell pneumonia associated with parainfluenza virus type 3 infection and chronic poliovirus type 2 meningoencephalomyelitis are documented in an infant with combined immunologic deficiency (Swiss type). Caution should be exercised in attributing cases of giant cell pneumonia to measles virus without serologic or ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(81)80032-9
更新日期:1981-05-01 00:00:00
abstract::Fibrillar proteins with a role in cellular shape and motility are present in the cytoplasm of most animal cells. They vary greatly in size, organization, and reactivity according to cell type and can be separately identified by the use of recently developed monospecific antisera and indirect immunofluorescence stainin...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(81)80026-3
更新日期:1981-05-01 00:00:00
abstract::Sections of synovium from 393 operations on diseased joints were re-examined without knowledge of the clinical findings. Specimens were scored for each of 37 histopathologic features. Independently, patients were assigned to one of 10 diagnostic groups after review of all available clinical data. Computer analysis rev...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(81)80141-4
更新日期:1981-04-01 00:00:00
abstract::To examine the hypothesis that malpositions of cardiac ventricles could be explained by altered development of the interventricular septum, we studied hearts from the Johns Hopkins Hospital autopsy files with double inlet left ventricle (16 cases) or corrected transposition (nine cases). In double inlet left ventricle...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(81)80125-6
更新日期:1981-03-01 00:00:00
abstract::An unusual case of acute respiratory obstruction caused by multicentric granular cell tumors of the laryngotracheobronchial tree is presented. The patient also had granular cell tumors in the tongue, vulva, and chest wall. Multiplicity of the lesions in the left lung and recurrent episodes of intercurrent pulmonary in...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(81)80132-3
更新日期:1981-03-01 00:00:00
abstract::The types of collagen present in a case of elastofibroma dorsi were determined using type specific, characterized collagen antibodies. The presence of type II collagen (normally present only in articular cartilage and in selected ocular structures) is discussed with regard to the pathogenesis of this lesion, and the u...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(81)80107-4
更新日期:1981-02-01 00:00:00
abstract::There is considerable interest in the role of the human wart virus in the pathogenesis of squamous cell carcinoma. Mucosal wart virus infections may produce considerable epithelial atypia and have eventuated in carcinoma in "normal" individuals in some instances. The verruciform lesions of patients with epidermodyspla...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(81)80108-6
更新日期:1981-02-01 00:00:00
abstract::Eight cases of primary mesenchymal renal tumor in infants under one year of age were studied. The patients' ages ranged from one day to seven months; all but one were diagnosed within the first three months of life. There were four typical congenital mesoblastic nephromas. Two malignant mesenchymal, one intermediate c...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(81)80244-4
更新日期:1981-01-01 00:00:00
abstract::A case of hemangiopericytoma arising in the esophagus is described. The light microscopic features were typical, and ultrastructural examination confirmed the presence of pericyte-like cells and excluded smooth muscle and fibroblastic differentiation. Areas of necrosis and a focus of mitotic activity within the tumor ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(81)80248-1
更新日期:1981-01-01 00:00:00
abstract::A 15 year old girl presented with a painful desquamative rash, fever, and profound hypotension. Despite antimicrobial therapy and intensive supportive measures, she died 80 hours after admission. The premortem skin biopsy and autopsy findings, which included subepidermal edema and blister formation, subacute vasculiti...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(81)80237-7
更新日期:1981-01-01 00:00:00
abstract::A 57 year old man presented with a two week history of right sided chest pain. An admission chest x-ray examination revealed a 2 by 1 cm. lytic lesion of the ninth right rib and right sided pleural effusion. The patient underwent a right thoracotomy during which 700 cc. of blood tinged pleural fluid was drained and a ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(80)80080-3
更新日期:1980-11-01 00:00:00